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Symbol
Name
ID

Casr
calcium-sensing receptor
MGI:1351351

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased circulating parathyroid hormone level	Elevated circulating parathyroid hormone level	Pancreatitis	Recurrent pancreatitis	Pancreatic adenocarcinoma	Increased circulating renin level	Parathyroid adenoma	Parathyroid carcinoma	Hyperparathyroidism	Primary hyperparathyroidism	Hurthle cell thyroid adenoma
Disease(s) Associated with CASR	Decreased circulating parathyroid hormone level	Elevated circulating parathyroid hormone level	Pancreatitis	Recurrent pancreatitis	Pancreatic adenocarcinoma	Increased circulating renin level	Parathyroid adenoma	Parathyroid carcinoma	Hyperparathyroidism	Primary hyperparathyroidism	Hurthle cell thyroid adenoma
autosomal dominant hypocalcemia 1
familial hypocalciuric hypercalcemia 1
hyperparathyroidism

Mouse Phenotypes		abnormal large intestine crypts of Lieberkuhn morphology	endocrine/exocrine gland phenotype	abnormal parathyroid gland chief cell morphology	enlarged parathyroid gland	parathyroid gland hyperplasia	pigmented parathyroid gland	abnormal pancreas morphology
Availability	Mouse Genotype	abnormal large intestine crypts of Lieberkuhn morphology	endocrine/exocrine gland phenotype	abnormal parathyroid gland chief cell morphology	enlarged parathyroid gland	parathyroid gland hyperplasia	pigmented parathyroid gland	abnormal pancreas morphology
	Casr^tm1Ces/Casr^tm1Ces
	Casr^{tm1b(KOMP)Mbp}/Casr⁺
	Casr^tm1Ces/Casr⁺		*
	Casr^tm1Wch/Casr^tm1Wch Tg(Vil1-cre)997Gum/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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